Founders

Gordon Horwitz of Allostatix LLC

How did you start your business?
I typically begin my business ventures by taking a few months to study the subject and pull together the business plan and investment strategy. For Allostatix, it was essential to find the best health researchers and statisticians in the local area. I found that in our chief science officer, Dr. Robert Ludke, from the University of Cincinnati's School of Public Health, and Dr. Ken Rothe, a seasoned statistician and neural network specialist.

Once my internal team was formed, it was necessary to create our Science Advisory Board to establish credibility in the health risk tool we were about to develop, as well as create a defensive moat around the IP we were developing.
It turns out that combination of certain biomarkers, when looked at interactively by a sophisticated analytic tool (which is what we have built), can predict disease and/or death in healthy people with a high accuracy, three to five years in advance.

How did you come up the idea for your business?
I’ve suffered from chronic fatigue since 1992 and just felt lousy most of the time. I have a great family physician, but the challenge for him was that all of my vitals and blood work were within the accepted, healthy range. Added to that, I am a spinning instructor so the question was, why was I feeling so lousy?

I set out on a personal quest to find out what was actually causing my early aging, tiredness, etc. I found what I was looking for when I was introduced to the concept of allostatic load. Allostatic load is the physical damage done to your body by chronic stress.

It was at one of the preliminary meetings with my research staff where we were discussing the allostatic load concept that I had my "aha!" moment; It became clear that my personal health challenges were being caused by the constant triggering of my body's automatic stress response. Once we had our health risk tool developed, I personally took the test and found that I had a high allostatic load. We deliver our Allostatix Load score on a color spectrum of green-yellow-red, and I scored in the red! Although all of my vitals and blood markers were within acceptable range when looked at independently, cumulatively analyzed they were telling a very different story. My body, as a whole, was out of balance.

What resources here did you take advantage of and how did they help?
I relied on my mentor and I believe everyone needs one. He kept me on a defined research track, helped me refine my business approach and led me to the University of Cincinnati. With the help of my research staff, I then developed an "engineering" spec for the screening test I was about to create, setting down the accuracy, sensitivity and predictive capabilities.

Once the allostatic load research was digested and our analytical engine developed, we moved into the Hamilton County Business Center incubator, which provided us with an enormous amount of business, sales, marketing and financial resources. Pat Long and HCBC helped us to refine our sales tool, presentations and investor pitches.

What inspires you?
Firstly, helping people have a healthier and happier life. Secondly, stopping the march toward chronic illness; I consider that a $2 billion, long-term threat to the United States. It is killing the country, no pun intended. Our risk tools can have a lasting and visible effect on this escalating number.

Interview by Robin Donovan